Up titrate the dose

Process of adjusting the dose of a medication

Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects.^[1]

When a drug has a narrow therapeutic index, titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small.^[2] Some examples of the types of drugs commonly requiring titration include insulin, anticonvulsants, blood thinners, anti-depressants, and sedatives.^[3][4][5]

Titrating off of a medication instead of stopping abruptly is recommended in some situations.

Titrating medication examples

Titrating medication examples

Opposite of titrate medication

Titration in pharmaceutical analysis pdf

Dose titration meaning

Down-titration of medication

Glucocorticoids should be tapered after extended use to avoid adrenal insufficiency.^[6]

Drug titration is also used in phase I of clinical trials. The experimental drug is given in increasing dosages until side effects become intolerable.^[7] A clinical trial in which a suitable dose is found is called a dose-ranging study.

See also

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References

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